
Ipriflavone
CAS No. 35212-22-7
Ipriflavone ( Osteofix )
Catalog No. M14200 CAS No. 35212-22-7
Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
500MG | 38 | In Stock |
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1G | 45 | In Stock |
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Biological Information
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Product NameIpriflavone
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NoteResearch use only, not for human use.
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Brief DescriptionIpriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.
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DescriptionIpriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.(In Vitro):Ipriflavone inhibits the proliferation and DNA synthesis of MDA-231 cells and blocks the ligand-induced phosphorylation of Tyr(845) of the EGFR. Ipriflavone does not promote apoptosis of MDA-231 cells. Ipriflavone also promotes the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like cells as well as the activity of alkaline phosphatase. (In Vivo):Daily oral administration of ipriflavone at 12 mg/mouse significantly inhibits the development of new osteolytic bone metastases and the progression of established osteolytic lesions, prolonging the life of tumor-bearing mice. Ipriflavone reduces the number of osteoclasts at the bone-cancer interface with no severe adverse effects on the host. 1-month treatment with ipriflavone increases bone density and improves the biomechanical properties of adult rat male bones without altering mineral composition.
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In Vitro——
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In Vivo——
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SynonymsOsteofix
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PathwayOthers
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TargetOther Targets
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Recptoradvanced glycation end products
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number35212-22-7
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Formula Weight280.32
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Molecular FormulaC18H16O3
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Purity>98% (HPLC)
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SolubilityEthanol: 2 mg/mL (7.13 mM); DMSO: 56 mg/mL (199.77 mM)
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SMILESO=C1C(C2=CC=CC=C2)=COC3=CC(OC(C)C)=CC=C13
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Chemical Name7-isopropoxy-3-phenyl-4H-chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cheng SL, et al. Calcif Tissue Int, 1994, 55(5), 356-362.
molnova catalog



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